For what it's worth I thought Alex and Jason seemed to "lock horns" over different perspectives on Science. I thought Jason was arguing that Science (The Method), is the best tool man has developed. I agree with that from the perspective that Science is a subset of "reality", and a reliable tool. In it's purest form the method yields measurable and repeatable results. Science and Magic don't need to be mutually exclusive, they both can exist, and neither has all the answer despite what some Materialists or Magicians may argue.
I thought Alex was arguing from the perspective of the negative consequences of the "miss-use" of the Scientific Method, i.e. where Science has negative consequences, either by mistake or worse for nefarious or political purposes. Both arguments are valid, but they are different arguments.
I obviously could be incorrect but that was the impression I had from the interview. Not bad overall but the level of confrontation prevented them from taking these interesting topics further. Alex did a good job of keeping his cool as Jason became emotional, which I think is understandable.
I listened to him on THC and Rune Soup and like many others wasn't sure what to make of him. This interview brought out the emotion in him, which I think demonstrates he is passionate and believes what he is preaching. That's a good thing, whether you agree or disagree with him.