I was borrowing Saiko's language for that post but "close approximation" is the way I think of it as well.
Saiko, Iyace is hitting on what I was trying to get at: the problem is not that science can't give us a full picture of reality, the problem is that some people seem to consider that to be a failure of science rather than a limitation of science. It is an unrealistic expectation and leads to anti-science sentiments.
Science is a tool. An extremely useful one but one that is not that easy to wield and has its limitations. Often its a two steps back one step forward process that can quite frustrating for some.
Once you come to terms with the fact that science will likely never present a complete picture (and that even if it does in some instances we have no way of knowing it anyway) then you can push that criteria aside and not worry about it any more. Our goal should be to continue pressing forward, expecting to stumble, reach dead ends, retrace our steps but take satisfaction in uncovering what we can, and adjusting as we go.